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ARW treatment was reported to enhance antioxidant defenses, moderate inflammation, improve cellular metabolism, and reduce hyperglycemia related adverse effects in this animal model

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"Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo"

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Thus, sertraline interferes with the function of the hypothalamicpituitarytesticular and hypothalamicpituitaryadrenal axes by affecting the wide distribution of serotonin receptors, thereby leading to reduced fertility in male rats (Figure 3)