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This is important as the lining prevents toxins and bacteria from escaping from the gut

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Antifungal and antibiofilm activities of bee venom loaded on chitosan nanoparticles: a novel approach for combating fungal human pathogens

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Future designs are likely to place more emphasis on rational simplification: after identifying one or two key TME barriers for a given indication, only functions that are closely aligned with those barriers would be retained, and embedded into carriers with mature manufacturing routes and well-characterized parameters [21]