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A number of clinical observations suggest that Down patients may have a functional folate deficiency despite having normal plasma levels of folate and vitamin B 12 [13]

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10.1021/bi051952q Biochemistry 176 PotapovA.YauW.-M.GhirlandoR.ThurberK

In a trial in anthracycline-treated patients at high risk for cardiac side effects, early treatment with enalapril was found to prevent the development of late cardiotoxicity (Cardinale 2006)

Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7