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The MDM2 inhibitor nutlin-3a suppresses abnormal T-cell expansion and reduces systemic inflammation in SLE models, highlighting an immunoregulatory role for MDM2 inhibition beyond oncology

ALC has been studied in various conditions including neurological and cognitive disorders, and cardiovascular disease, as well as with respect to the fatigue and pain associated with conditions such as chronic fatigue syndrome and sciatica

Toxicity is extremely rare

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