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Many patients begin to see noticeable changes in their energy levels and body composition within a few weeks of starting the injections

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Maintenance Phase: Once adequate B12 levels are achieved, the frequency of injections can be reduced

The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

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