doi: 10.1016/j.freeradbiomed.2022.12.105 18
The expression of autophagy genes is increased in HepG2 ATP7B-KO and PHH WD cells To validate the copper-dependent gene regulation in HepG2 and HepG2 ATP7B-KO cells, both were cultured in RPMI medium, contrasting with the GSE107323 dataset, which used DMEM and RPMI medium, respectively
While these pancreatic multi-omics resources offer unprecedented resolution of intra-organ heterogeneity, they remain focused almost exclusively on the pancreas and currently do not include matched profiles of the gut microbiome, despite the growing recognition of the gutpancreas axis in metabolic disease

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