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In addition, DM can cause abnormal sperm motility, testicular alterations, decreased libido, impotence, erectile dysfunction, and hormone abnormalities that result in subfertility and infertility in men []

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The hypothesis that GSSG functions as the oxidant for class III peroxidases during ROS production in apoplast, however, is not consistent with previous observations that a GSH peak was not observed in a bean apoplastic fluid before and after an oxidative burst and glutathione was less effective for the production of reactive oxygen species than free cysteine in an in vitro assay 37,38

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At the same time, the JAK-STAT pathway, triggered by interferons, induces interferon-stimulated genes (ISGs) with antiviral effects