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Hence, these thiomethyl metabolites have the potential to be used as diagnostic signals to study susceptibility to hepatotoxicity related to inter-individual production of NAPQI in these types of clinical investigations

Manganese contributes to the protection of cells against oxidative stress and additionally plays a role in maintaining healthy bones and is involved in the formation of connective tissue as well as in energy metabolism

This is also consistent with earlier studies showing that cystine starvation activates GCN2 rather than PERK 47 and the lack of enhanced splicing of the XBP1 mRNA upon erastin treatment 9

Curr Allergy Asthma Rep 14(1):404