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In addition to structural regulation at the mitochondrial level, cells utilize CMA as a selective mechanism for mitochondrial protein clearance

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Therefore, these results indicate that the inhibition of NF-B pathway contributes to promote SGNs survived from peroxynitrite injury, and that GPX1 protects SGNs against peroxynitrite-induced damage, at least in part, via blocking the NF-B pathway activation

meQTL and ncRNA functional analyses of 102 GWAS-SNPs associated with depression implicate HACE1 and SHANK2 genes

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