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It has also been shown to lower homocysteine levels, a molecule linked to inflammation and cognitive decline, with longitudinal studies linking optimal B12 levels with improved cognitive function, mood and reduced risk of neurodegenerative disease

For example, a musculoskeletal model might follow changes in tissue histology and movement patterns, while a gut-focused model could track barrier integrity, local signaling markers, or microbiome shifts

If other vitamin deficiencies are present, they should be treated

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For athletes, it aids oxygen delivery to muscles and boosts endurance