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The peptide works through several mechanisms: it upregulates growth factor expression (particularly VEGF), promotes angiogenesis (the formation of new blood vessels at injury sites) [5,12] , modulates the nitric oxide system, and supports the FAK-paxillin pathway, which governs cell migration to damaged tissue
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This has enabled deeper investigation into molecular mechanisms and peptide-mediated biological processes
These actions are likely due to the potential of BPC-157 to simulate vasodilatation and angiogenesis (new blood vessel formation) due to its action on peptidergic growth factors such as endothelial growth factor, Consequently, the peptide has demonstrated significant protective effects against gastric mucosal injury in rat models
