Injection Site: Rotate your injection sites (stomach, thighs, or upper arms) daily to prevent the breakdown of local fat tissue
Oral supplements, on the other hand, must go through your digestive system, which can be affected by your health and other nutrients
In obesity and metabolic dysfunction, NNMT is often overexpressed in adipose tissue, depleting nicotinamide and lowering NAD+ availability [2]
However, it is so important to talk to your doctor first, especially if you have any underlying medical conditions or take medications
Changes in brain insulin metabolism and insulin resistance are associated with several CNS disorders such as Alzheimers disease (AD), depression [71,72,73], autism [74], schizophrenia [75], Huntingtons disease [76], Parkinsons disease (PD) [77], etc