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Int J Chron Obstruct Pulmon Dis

Finally, translational progress is bottlenecked by the lack of strategies to selectively manipulate p53s ferroptosis-regulating activity: activating its pro-ferroptotic function in cancer cells while preserving its anti-ferroptotic role in normal tissues remains a major challenge, and no validated biomarkers exist to predict which tumors will respond to p53-targeted ferroptosis therapies

Glutamate and its receptors in cancer

Journal of Physiology, 555 (3), 589606

This stress can cause a decrease in the production of inflammatory cytokines like TNF- and interleukins (such as IL-6, IL-10, and IL-1), ultimately leading to the death of these cells