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TRAKA, M., GASPER, A

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In animal models, berberine exhibited statin-like effects by reducing LDL and total cholesterol levels as well as aortic lesions, and improved glucose tolerance while reducing glucose levels, weight gain, and adipose tissue (3)

These findings clearly show that GPX1 is irreplaceable by other selenoproteins in protecting against systemic oxidative stress, and GPX1 has a significant antioxidant function in the body ( FIGURE 1 On the surface, the mice after GPX1 KO performed normally, but these mice were susceptible to the production of oxidative substances, and when stimulated, they were easy to cause harm to mice and increase oxidative stress in vivo