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doi: 10.1007/s40618-014-0097-2 16 PapiGCorselloMSPontecorviA

Sighs are reported to result from activation of a neuronal circuit in the preBtzinger complex/parafacial group 133 while apnea results from direct inhibition of the preBtzinger complex or inhibition of drive to phase-switching neurons in the preBtzinger complex 134

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Osteoarthritis: By promoting cartilage metabolism and reducing inflammatory cytokines, peptides offer a regenerative alternative to repeated corticosteroid injections that can accelerate cartilage degradation