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Infections in standard or tapered dose of prednisolone for alcohol-associated hepatitis: a randomized trial (STASH trial)

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This matters for dosing because beta-3 receptor sensitivity varies throughout the day and in response to nutritional status

The Nrf-2 is another target for preventing cardiac oxidative stress 16

The study found that microplastics (MPs) in systemic circulation can be phagocytosed by cells and induce capillary occlusion in the cerebellar cortex, these thromboembolic occlusions reduce blood flow and trigger neurological dysfunction in mice, the mechanism reveals that MPs indirectly impair tissue function by mediating cellular occlusion and disrupting local microcirculation, rather than directly penetrating tissues (66)