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Recent studies of peptide-bound, active, Gs-coupled, structures of CTR or AMYRs provide evidence supporting distinct conformations of receptors when bound to CT peptides versus amylin peptides 15 that may contribute to pharmacological differences between dual CTR and AMYR agonists

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The peptide's demonstrated safety in gastric juice stability and lack of toxic effects across wide dose ranges support its potential for gastrointestinal therapeutic applications pending further clinical validation

Both are being discussed and in some cases sold online, raising serious patient safety concerns

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