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Although xCT expression is confined to the plasma membrane in normal tissues (36,39), it is upregulated in certain types of cancer, such as colorectal cancer, malignant glioma and non-small cell lung cancer, which increases cystine uptake (4042)

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Hu Y, Chen D, Zheng P, Yu J, He J, Mao X et al (2019) The bidirectional interactions between resveratrol and gut microbiota: an insight into oxidative stress and inflammatory bowel disease therapy

MTs could also attenuate the stress in this organelle by providing intramolecular Zn to recover the normal folding of ER proteins

Gln is transported to cells where it acts as a starting material for the production of different amino acids, proteins, nucleotides, and other important biological molecules