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A reasonable titration schedule might look like this: Week 1: 200mcg once daily Week 2: 300mcg once daily Week 3 onward: 300-500mcg based on response and tolerance Optimizing injection technique Poor injection technique contributes to injection site reactions and potentially to other effects like nausea from anxiety around the process

Combined sample size is roughly 30 patients

For most injuries, such as ligament sprains or muscle strains, users typically feel relief within this 2-4 week timeframe