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Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

Lactobacillus Rhamnosus GG derived extracellular vesicles modulate gut microbiota and attenuate inflammatory in DSS-induced colitis mice

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doi: 10.3390/antiox9080725 220 XuXOcanseyDKWPeiBZhangYWangNWangZet al

The genius of the LR3 modificationsubstituting an Arginine for a Glutamic Acid at the third position and adding a 13 amino acid extension peptideis that it dramatically reduces its affinity for these binding proteins