While oral supplements are available, B12 injections are often considered more effective because they deliver the vitamin directly into the bloodstream for improved absorption
The choice of treatment should be individualised, considering the underlying cause, symptom severity, patient preference, and practical factors such as access to healthcare facilities for regular injections
Researchers should consult primary literature for protocol-specific concentrations in their experimental model
Proton pump inhibitors (PPIs) and H2-receptor antagonists, used for acid reflux, reduce stomach acid production, which can impair dietary B12 absorption, though this does not directly affect injections
Benefits of subcutaneous administration include: Easier for patients to give themselves injections Less risk of muscle irritation Potential for slower absorption, depending on the injection site Intravenous (IV) Usage in Clinical Settings Intravenous Vitamin B12 is usually used for severe deficiency cases or when quick correction is needed
