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[ 425 ] This implies that even for the same disease, the function of BACH1 in different tissue cells might be distinct, and in the future treatment strategy of the disease, targeted intervention of BACH1 expression levels in specific cells is essential ( Table 2 )

In the more common relapsingremitting form of MS, if an ongoing acute/adaptive immune response were the primary driver of later progression, atrophy and disability, it would stand to reason that there should be a strong correlation between inflammatory relapses and disability throughout the disease course

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10.1016/j.tem.2008.12.002 Trends Endocrinol

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