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In this canine model, it was found that pyridoxine is useful in postponing the onset and severity of PPES (145)

infantum , which strongly parasitizes canine skin, and people in contact with infected dogs can be infected

constructed a nano-peptitde with a 3060 nm particle size, encapsulating leucine5-enkephalin hydrochloride (LENK), and proved this nanoparticle was able to transport LENK through intranasal administration (Fig

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However, despite the good pharmacological properties shown by this molecule on several cancers, its use in the clinic is problematic because of its strong diuretic properties