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Elizabeth Rebello of the University of Texas MD Anderson Center

If you experience any of these symptoms after receiving a B12 injection, you should seek medical attention immediately

Furthermore, during a stroke or heart attack episode, when the clogged artery is unblocked to save the patient, a sudden flow of oxygen (reperfusion) causes significant damage of the tissue via the oxidative stress process

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Signs include persistent fatigue, paraesthesia (pins and needles) in hands and feet, difficulty with balance, memory problems, mood disturbances, and megaloblastic anaemia