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Given that for GSH the strongest interactions are formed by the C-terminus of the ECG tripeptide, the binding of CG is not unexpected, the preference for GSH, however, confirms that additional binding energy is contributed by residue E, although its side chain can assume multiple conformations (Fig

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Considering that IGF-1 regulates IGFBP-1 and IGFBP-2, it is reasonable to conclude that early changes in insulin resistance alter their concentrations