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As IC/BPS might be multifactorial, future research should target different implicated pathways simultaneously and study the role of reactive oxygen species as a root cause in IC/BPS

Nature 355(6359):441446 [DOI] [PubMed] [Google Scholar] Zheng J-N, Zhuo J-Y, Nie J, Liu Y-L, Chen B-Y, Wu A-Z, Li Y-C (2021) Phenylethanoid glycosides from Callicarpa kwangtungensis Chun attenuate TNF--induced cell damage by inhibiting NF-B pathway and enhancing Nrf2 pathway in A549 cells

Evidence on how thymic function influences tumor cell biology and response of patients with cancer to therapies remains unsatisfactory, although there has been some improvement in the knowledge provided by recent studies

Melatonin potentiates chemotherapy-induced cytotoxicity and apoptosis in rat pancreatic tumor cells

While human data is limited, BPC-157 has been shown in animal studies to improve myogenesis and muscle fiber regeneration in rats with quadriceps transection, muscle crush injury, and corticosteroid-impaired healing