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Studies have shown that oral collagen can be absorbed at rates as high as 63%, compared to 1-2% for other oral peptides.12 13 Injectable collagen peptides are available, too, but surveys show a large proportion of the population would prefer a less invasive method.14 BPC-157 is another peptide that boasts good oral bioavailability, but the same cant be said about its frequent companion, TB4.15 16 Because we recommend BPC-157 and TB4 in combination, and because BPC-157 can be hard to find in oral form, BPC alone failed to earn our designation as the easiest-to-use peptide
The antioxidant effect of glutathione has been proven to prevent inflammation in synovial fibroblasts, joint connective tissue cells
The physiological concern with any bioactive peptide used chronically is receptor desensitization, metabolic accumulation of degradation byproducts, and potential downstream endocrine effects that manifest only after sustained signaling pathway activation
