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BPC-157 - 5mg BPC-157 is a 15-amino-acid synthetic peptide used in preclinical research models to investigate cellular repair mechanisms, extracellular matrix dynamics, vascular signaling, and tissue stress responses

However, the largest Phase IIb trial involving 536 subjects failed to demonstrate statistically significant weight loss compared to placebo at the primary 12-week endpoint, leading Metabolic Pharmaceuticals to terminate development in 2007

doi: 10.15252/embr.202051034 10

Patients completed the self-reported Quality of Life in Neurological Disorders (Neuro-QoL) battery (including measures for anxiety, depression, cognitive function, emotional and behavioral dyscontrol, positive affect and well-being, and ability to participate in/satisfaction with social roles)

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