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DCN is released from early-stage ferroptotic cells via lysosomal exocytosis and damaged plasma membranes, binding to AGER on macrophages

In this condition, it can be safely stored at a controlled room temperature, which is typically defined as 20C to 25C (68F to 77F)

A subcutaneous injection creates a local depot from which the compound is absorbed into capillaries and lymphatics over time, generally producing a slower rise and a more gradual exposure than an intravenous bolus

increased albumin elimination in the urine

A 15mcg error on a 50mcg intended dose represents 30% variance, which makes comparing results across injection days statistically meaningless