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LOXs (EC 1.13.11.x) are non-heme iron, or sometimes manganese-dependent enzymes, that catalyze the regio- and enantioselective dioxygenation of polyunsaturated fatty acids (PUFAs) leading to the formation of fatty acid hydroperoxides (FAHPs) (Fig

Although these approaches have not been incorporated into official asthma management guidelines, numerous case reports describe clinical improvement following their use