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Gout, a painful arthritic condition caused by the deposition of urate crystals in joints, is one of the most widely recognized consequences of elevated UA levels
One domain senses the glutathione, and the other transports it." The protein's unique structure may explain its abilities, says Birsoy
Large-scale gene expression profiling reveals major pathogenetic pathways of cartilage degeneration in osteoarthritis
Although their etiologies vary, these diseases are commonly associated with a severe disruption of the local pathological microenvironment (PME) during their progression