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Mitochondrial dysfunction contributes to excessive production of mitochondrial ROS and mutations in mtDNA, further exacerbating oxidative stress

Clinical outcomes from the PARAMEDIC2 trial are summarized, showing higher rates of ROSC in the epinephrine group (36.3%) compared with placebo (11.7%), a modest increase in 30-day survival, but a higher proportion of survivors with severe neurological impairment (31.0% vs

Pair that with a Certificate of Analysis, and researchers get a documented paper trail showing exactly what theyre working with, batch by batch

The key compound the brain produces that stimulates neurogenesis is called brain derived neurotrophic growth factor (BDNF)

doi:10.1016/j.jconrel.2011.01.030