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In addition, Liver cancer is more dependent on FSP1 overexpression mediated by Keap1/Nrf2 to inhibit ferroptosis, and using FSP1 inhibitor iFSP1, FSP1 effectively induces ferroptotic cell death in liver cancer and profoundly increased immune infiltrates to unleash anti-cancer immune response (Cheu et al., 2023)

The treatment employs focused beams of light that penetrate the skins layers to break down melanin clusters and promote an even tone