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Research (168) indicates that the Fe 2+ directly induced by myoglobin metabolism may lead to lipid peroxidation in proximal tubule epithelial cells, which could be an important pathogenic mechanism of rhabdomyolysis-induced acute AKI

Disulfide-containing high mobility group box-1 promotes N-Methyl-d-Aspartate receptor function and excitotoxicity by activating toll-like receptor 4-dependent signaling in hippocampal neurons

The scientists believe a vaccine approach could have an advantage over current opioid addiction therapies because it would not alter brain chemistry like many of todays anti-addiction therapies do

doi: 10.1371/journal.pone.0107111

Farswan, M., Rathod, S