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Additionally, integration of gene expression data has identified 269 differentially expressed programmed cell death-related genes (DPGs) in endometriosis, with 17 showing causal associations and three (TNFSF12, AP3M1, PDK2) emerging as potential diagnostic biomarkers ( Epigenetic dysregulation plays a central role, involving DNA methylation, histone modifications, and non-coding RNAs

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