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Catalpol alleviates Ang II-Induced renal injury through NF-B pathway and TGF-1/Smads pathway

doi:10.1186/1475-2859-12-87 Ayer A, Gourlay CW, Dawes IW (2013) Cellular redox homeostasis, reactive oxygen species and replicative ageing in Saccharomyces cerevisiae

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While research suggests it is safe and well-tolerated in short-term studies when administered in carefully controlled pulses, its unapproved status means: Long-Term Effects are Unknown: The full impact of chronic use on cardiovascular health, glucose regulation, or promotion of latent malignancies is not fully established via large-scale human trials