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Metabolic bone disease in children with transfusion-dependent thalassemia

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Moreover, TQ had inhibited the migration of metastatic human (A375) and murine (B16F10) melanoma cells by suppressing NLRP3 inflammasome activation and reducing caspase-1 cleavage [28]

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However, the relevance of these findings to humans are unclear since the long-isoform receptor of leptin is present in fetal pituitaries and in pituitary tumors developed during postnatal life, but absent in pituitaries obtained from normal subjects postnatally [36]