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J Biol Chem 273:2252822536 Dean O, Bush AI, Berk M, Copolov DL, van den Buuse M (2009) Glutathione depletion in the brain disrupts short-term spatial memory in the Y-maze in rats and mice

Starting both agents at lower doses than typically used for monotherapy and escalating more slowly can improve tolerability

doi: 10.1146/annurev.pharmtox.46.120604.141046

Those who experience a B12 deficiency due to issues absorbing B12 Aside from the typical symptoms of B12 deficiency, developing more serious or long-lasting complications is possible

However, it is equally important to note that meaningful progress is possible at any age and that it is never too late to begin therapy