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At 24, 48 and 72 hours, glutathione synthetase activity increased in susceptible plants, but the increase was of a much smaller magnitude in comparison with that observed in resistant plants

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In conclusion, our data suggest that GSSG is a potent and clinically relevant sensitizer for TNF-induced hepatotoxicity in NAFLD, which represents a potential therapeutic target for NAFLD

10.1016/j.biopha.2020.111121 115 LoguercioC.AndreoneP.BriscC.BriscM

MAM is a consultant for Boehringer-Ingelheim, SoseiHeptares, and Neurocrine and sits on the advisory board for Quolet