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Apr 2017;36:79-84

Kumar, K., Mehra, R., Guin, R

Cellular effects duration vs plasma half-life Critical distinction: Plasma half-life duration of effects GHK-Cu clears blood in hours But cellular effects last days How GHK-Cu works: Peptide binds to cell surface receptors Triggers intracellular signaling cascades Activates gene expression changes Initiates collagen synthesis, wound healing, etc

CONCLUSIONS To address the chronic disease of obesity, it is of utmost importance to develop novel, safe, and effective AOMs

AOD9604 is a 16-amino acid fragment corresponding to positions 176-191 of the human growth hormone sequence, isolated for its lipolytic activity while being structurally distinct from the growth-promoting domain