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A 2021 randomized controlled trial published in Diabetes Care (N=105) compared dulaglutide 1.5 mg weekly against glimepiride over 24 weeks in adults with type 2 diabetes and found that dulaglutide significantly reduced plasma malondialdehyde (a lipid peroxidation marker) and raised superoxide dismutase activity

The combination exists primarily in wellness marketing and patient-initiated stacking practices rather than in peer-reviewed research

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