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639 Despite early study termination (clinical hold) by the US Food and Drug Administration, fulranumab treatment resulted in dose-dependent efficacy and was generally well tolerated

acute liver failure study group: Lowering the risks of hepatic failure

It helps reduce signs of tanning and corrects uneven skin tone from the first use, and is suitable for all skin types including sensitive skin

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They further developed a diagnostic model, OAMGS, based on four marker genes (VEGFA, CDKN1A, PIM3, MAFF) using machine learning, validated in both human and rat models (Lin et al., 2025)