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Upon binding, IGF-1R activates two downstream pathways: the PI3K/Akt pathway (driving protein synthesis and glucose uptake) and the MAPK/ERK pathway (promoting cell proliferation and differentiation)

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Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N

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Additionally, improvement in experimental designs for long-term and chronic studies may help comprehend immunogenic responses to prolonged plastic exposure