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The success of peptide drugs in rare disease applications has demonstrated the value of orphan drug programs in bringing innovative therapies to patients with limited treatment options

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TB-500 is a synthetic peptide designed to mimic aspects of Thymosin Beta-4 activity, functioning through actin regulation, promoting cell migration and anti-inflammatory responses

G6PD deficiency in newborn infants is well-recognized to cause a sudden rise in bilirubin levels that in many cases only exchange transfusion may be able to rapidly alleviate the toxicity from bilirubin accumulation

Age-dependent decline of motor neocortex but not hippocampal performance in heterozygous BDNF mice correlates with a decrease of cortical PSD-95 but an increase of hippocampal TrkB levels