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The cancelled 2015 Phase I trial (NCT02637284) was almost certainly abandoned for this reason rather than buried by a regulator

found that, in addition to the anti-ferroptotic actions of electroconvulsive therapy (ECT), it also increased BDNF expression in a rat model of chronic, unpredictable mild stress [142]

Mechanistically, sodium butyrate down-regulates SLC7A11 transcription by modifying ATF3 expression ( Tirapazamine (TPZ), a hypoxic prodrug, is renowned for its antitumor effects in the hypoxic tumor microenvironment

Acute airway inflammation, leading to a variable form of AHR, is usually reversed by inhaled glucocorticosteroids (ICS)

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