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HDAC inhibition also rescued the DNA repair response in iPSC-derived motor neurons carrying the ALS associated FUS P525L mutation

Symptoms Severe vitamin E deficiency results mainly in neurologic symptoms, including impaired balance and coordination (spinocerebellar ataxia), injury to the sensory nerves (peripheral neuropathy), muscle weakness (myopathy), and damage to the retina of the eye (retinopathy)

doi: 10.1093/humrep/des303 38 FakeyeT

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During the final purification step of peptide synthesis (usually RP-HPLC), acids like trifluoroacetic acid (TFA) or acetic acid are used