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Acta 461 , 4146 (2016)

50 AT-II has a pivotal role not only in the progression of tubulointerstitial injury but also in obstructive nephropathy

The fetal liver exhibited higher mitochondrial activity and increased mitochondrial DNA copy numbersboth indicative of enhanced energy metabolismwithout major shifts in gene expression, suggesting that regulation may occur at the protein level (Safain et al., 2025)