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Increased 8-hydroxy-2'-deoxyguanosine in leukocyte DNA in Lebers hereditary optic neuropathy

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666 Ultra-high performance liquid chromatography-mass spectrometry analysis showed that moderately controlled cortical impact induces significant expression of PUFA in mouse serum, leading to lipid peroxidation and ferroptosis

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SASP factors as IL-6 may be the cause for the observed loss in renal function and we wondered how FOXO4-DRI would function under such high-SASP conditions