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A recent press release reported topline results indicating that tirzepatide met the primary objective of noninferiority compared with dulaglutide for time to first occurrence of death from cardiovascular causes, nonfatal myocardial infarction or nonfatal stroke (HR 0.92, 95.3% CI 0.831.01), along with a reduction in all-cause mortality (HR 0.84, 95% CI 0.750.94)

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Chronic elevation of these free radicals will deplete GSH/GSSG redox/antioxidant capacity, allowing unopposed free-radical generation and a self-perpetuating cycle, leading to chronic oxidative stress and damage

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