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doi: 10.1016/j.jhep.2008.08.009 14 AntoniadesCGKhamriWAbelesRDTaamsLSTriantafyllouEPossamaiLAet al

Methanol was added to extract a yellowish sediment, which was then dissolved and re-precipitated with methanol several times until the pH was less than or equal to 7.5

For observational studies in Table 1 ( n = 11), formal standardized risk of bias assessment was not conducted due to substantial heterogeneity in study designs, participant characteristics, laboratory methods, and outcomes measured

While not direct drug side effects, these changes occur in the context of treatment and may be perceived as medication-related